Concepedia

Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: Synthesis, pharmacological evaluation, and cross-target QSAR studies

Herman D. Lim, Enade Perdana Istyastono, Andrea van de Stolpe, Giuseppe Romeo, Silvia Gobbi, Marjo Schepers, Roger Lahaye, Wiro M.B.P. Menge, Obbe P. Zuiderveld, Aldo Jongejan,

Bioorganic & Medicinal Chemistry · 2009 · 34 citations · 19 references

Open access

References

19

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

Thomas A. Halgren · Journal of Computational Chemistry · 1996 · 5.3K citations

Natural Sciences, Biophysics, Computational Chemistry +12

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

Johann Gasteiger, Mario Marsili · Tetrahedron · 1980 · 4.1K citations

Natural Sciences, Chemistry, Physics +10

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

Jean‐Michel Arrang, M. Garbarg, Jean‐Charles Schwartz · Nature · 1983 · 1.6K citations

Life Sciences, Neuroscience, Pharmacology +14

Prediction of Physicochemical Parameters by Atomic Contributions

Scott A. Wildman, Gordon M. Crippen · Journal of Chemical Information and Computer Sciences · 1999 · 1.5K citations

Natural Sciences, Chemistry, Computational Chemistry +15

y-Randomization and Its Variants in QSPR/QSAR

Christoph Rücker, Gerta Rücker, Markus Meringer · Journal of Chemical Information and Modeling · 2007 · 937 citations

Pharmacy, Biostatistics, Medicinal Chemistry +14