Concepedia

A Subsequent Human Neural Progenitor Transplant into the Degenerate Retina Does Not Compromise Initial Graft Survival or Therapeutic Efficacy

Bin Lü, Yanhua Lin, Yu-Chun Tsai, Sergey Girman, Grażyna Adamus, Melissa K. Jones, Brandon Shelley, Clive N. Svendsen, Shaomei Wang

Translational Vision Science & Technology · 2015 · 16 citations · 44 references

DOIFull text

Open access

Abstract

Redosing neural progenitors do not affect the efficacy of the initial grafts in protecting vision or induce unwanted immune responses.

References

44

Immunogenicity of induced pluripotent stem cells

Tongbiao Zhao, Zhen‐Ning Zhang, Zhili Rong et al. · Nature · 2011 · 1.4K citations

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Embryonic stem cell trials for macular degeneration: a preliminary report

Steven D. Schwartz, Jean‐Pierre Hubschman, Gad Heilwell et al. · The Lancet · 2012 · 1.4K citations

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Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

Fred H. Gage, Penelope W. Coates, Theo D. Palmer et al. · Proceedings of the National Academy of Sciences · 1995 · 1K citations · Full text

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CD25+CD4+ Regulatory T Cells Prevent Graft Rejection: CTLA-4- and IL-10-Dependent Immunoregulation of Alloresponses

Cherry Kingsley, Mahzuz Karim, Andrew Bushell et al. · The Journal of Immunology · 2002 · 746 citations · Full text

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

Artur V. Cideciyan, Tomás S. Alemán, Sanford L. Boye et al. · Proceedings of the National Academy of Sciences · 2008 · 660 citations · Full text

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