Concepedia

The immunogenicity of the 7E3 murine monoclonal Fab antibody fragment variable region is dramatically reduced in humans by substitution of human for murine constant regions

David Knight, Carrie Wagner, Robert E. Jordan, Mary Frances McAleer, Renato DeRita, David N. Fass, Barry S. Coller, Harlan F. Weisman, John Ghrayeb

Molecular Immunology · 1995 · 95 citations · 37 references

DOI

Concepts

References

37

Use of a Monoclonal Antibody Directed against the Platelet Glycoprotein IIb/IIIa Receptor in High-Risk Coronary Angioplasty

The EPIC Investigators · New England Journal of Medicine · 1994 · 2.6K citations · Full text

, , +17

Handbook of Experimental Immunology.

Annals of Internal Medicine · 1968 · 2.4K citations · Full text

, , +12

Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.

Sherie L. Morrison, M J Johnson, L A Herzenberg et al. · Proceedings of the National Academy of Sciences · 1984 · 1K citations · Full text

, , +17

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

Barry S. Coller, Ellinor I.B. Peerschke, L E Scudder et al. · Journal of Clinical Investigation · 1983 · 763 citations · Full text

, , +17

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.

Barry S. Coller · Journal of Clinical Investigation · 1985 · 590 citations · Full text

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