L E Scudder

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

Barry S. Coller, Ellinor I.B. Peerschke, L E Scudder et al. · Journal of Clinical Investigation · 1983 · 761 citations · Full text

Immunology, Molecular Biology, Inflammation +23

Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GPIIb/IIIa receptor. Correlation with bleeding time, platelet aggregation, and blockade of GPIIb/IIIa receptors.

Barry S. Coller, John D. Folts, Susan R. Smith et al. · Circulation · 1989 · 244 citations

Immunology, Pharmacotherapy, Platelet Aggregation +20

Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogs.

Tsunehiro Yasuda, Herman K. Gold, John T. Fallon et al. · Journal of Clinical Investigation · 1988 · 243 citations · Full text

Immunology, Thrombosis, Hematology +16

Thromboerythrocytes. In vitro studies of a potential autologous, semi-artificial alternative to platelet transfusions.

Barry S. Coller, K. Springer, Jürg H. Beer et al. · Journal of Clinical Investigation · 1992 · 111 citations · Full text

Mixed Aggregates, Engineering, Rgd Peptides +25

Rapid and Simple Platelet Function Assay to Assess Glycoprotein IIb/IIIa Receptor Blockade

Barry S. Coller, Daniel G. Lang, L E Scudder · Circulation · 1997 · 109 citations