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An Mll–AF9 Fusion Gene Made by Homologous Recombination Causes Acute Leukemia in Chimeric Mice: A Method to Create Fusion Oncogenes

Javier Corral, Isabelle Lavenir, Helen Impey, Alan J. Warren, A. Förster, Teresa Larson, Sarah E. Bell, Andrew N. J. McKenzie, Gareth King, Terence H. Rabbitts

Cell · 1996 · 533 citations · 23 references

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23

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Gérard I. Evan, George K. Lewis, Gary Ramsay et al. · Molecular and Cellular Biology · 1985 · 2.4K citations

, , +14

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

, , +15

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Douglas Tkachuk, Sabine Köhler, Michael L. Cleary · Cell · 1992 · 932 citations

, , +16

Altered Hox expression and segmental identity in Mll-mutant mice

Benjamin Yu, Jay L. Hess, Susan Horning et al. · Nature · 1995 · 880 citations

, , +11