Concepedia

Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: A comparison with diazepam and buspirone

Katsuya Harada, Masaki Aota, Tatsuo Inoue, Ritsuko Matsuda, Takuma Mihara, Takayuki Yamaji, Koji Ishibashi, Nobuya Matsuoka

European Journal of Pharmacology · 2006 · 82 citations · 35 references

DOI

Concepts

References

35

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

, , +9

Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines

Jacqueline N. Crawley, Frederick K. Goodwin · Pharmacology Biochemistry and Behavior · 1980 · 1.4K citations

, , +13

Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors

María Pompeiano, José Palacios, Guadalupe Mengod · Molecular Brain Research · 1994 · 877 citations

, , +13

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

Sandra E. File · Journal of Neuroscience Methods · 1980 · 818 citations

, , +5