Early-onset Parkinson’s disease associated with a new parkin mutation in a Spanish family

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Tohru Kitada, Shuichi Asakawa, Nobutaka Hattori et al. · Nature · 1998 · 5.2K citations

Life Sciences, Genetics, Molecular Genetics +10

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Hideki Shimura, Nobutaka Hattori, Shinichiro Kubo et al. · Nature Genetics · 2000 · 2K citations

Life Sciences, Molecular Biology, Neuroscience +14

Association between Early-Onset Parkinson's Disease and Mutations in the<i>Parkin</i>Gene

Christoph B. Lücking, Alexandra Dürr, Vincenzo Bonifati et al. · New England Journal of Medicine · 2000 · 1.4K citations · Full text

Life Sciences, Genetics, Neurology +14

Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Yi Zhang, Jun Gao, Kenny K. K. Chung et al. · Proceedings of the National Academy of Sciences · 2000 · 979 citations · Full text

Life Sciences, Genetics, Neuroscience +17

A Wide Variety of Mutations in the Parkin Gene Are Responsible for Autosomal Recessive Parkinsonism in Europe

N. Abbas, C.B. Lücking, Sylvain Ricard et al. · Human Molecular Genetics · 1999 · 533 citations

Life Sciences, Genetics, Molecular Genetics +17