Biochemical, Functional, and Pharmacological Characterization of AT-56, an Orally Active and Selective Inhibitor of Lipocalin-type Prostaglandin D Synthase

Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

Hiroyuki Hirai, Kazuya Tanaka, Osamu Yoshie et al. · The Journal of Experimental Medicine · 2001 · 1.1K citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Immunology +17

Prostaglandin D ₂ as a Mediator of Allergic Asthma

Toshiyuki Matsuoka, Masakazu Hirata, Hiroyuki Tanaka et al. · Science · 2000 · 736 citations

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

Robert A. Lewis, Nicholas A. Soter, P T Diamond et al. · The Journal of Immunology · 1982 · 587 citations · Full text

Inflammatory Lung Disease, Human Growth, Mast Cell Disorder +20

CRTH2, an orphan receptor of T‐helper‐2‐cells, is expressed on basophils and eosinophils and responds to mast cell‐derived factor(s)

Kinya Nagata, Hiroyuki Hirai, Kazuya Tanaka et al. · FEBS Letters · 1999 · 293 citations · Full text

Mast Cell Disorder, Immune Regulation, Immunology +23

Cloning and Crystal Structure of Hematopoietic Prostaglandin D Synthase

Yoshihide Kanaoka, Hideo Ago, E. Inagaki et al. · Cell · 1997 · 259 citations · Full text

Crystal Structure, Biosynthesis, Aldo-keto Reductase +4