Concepedia

Activation of NFκB is inhibited by curcumin and related enones

Waylon Weber, Lucy A. Hunsaker, C. Nathaniel Roybal, Ekaterina Bobrovnikova-Marjon, Steven F. Abcouwer, Robert E. Royer, Lorraine M. Deck, David L. Vander Jagt

Bioorganic & Medicinal Chemistry · 2005 · 116 citations · 44 references

DOI

Concepts

References

44

Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane)

Sanjaya Singh, Bharat B. Aggarwal · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

, , +12

Assessment of Antioxidant Activity by Using Different In Vitro Methods

K. Schlesier, M. Harwat, Volker Böhm et al. · Free Radical Research · 2002 · 838 citations

, , +16

Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity.

Christian Jobin, Cynthia A. Bradham, Maria Pia Russo et al. · PubMed · 1999 · 720 citations

, , +17

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

Alok C. Bharti, Nicholas J. Donato, Sujay Singh et al. · Blood · 2003 · 683 citations · Full text

, , +17

Curcumin Blocks Cytokine-Mediated NF-κB Activation and Proinflammatory Gene Expression by Inhibiting Inhibitory Factor I-κB Kinase Activity

Christian Jobin, Cynthia A. Bradham, Maria Pia Russo et al. · The Journal of Immunology · 1999 · 675 citations · Full text

, , +17