Concepedia

Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma

Takatomo Koshiba, Ryo Hosotani, M. Wada, Yoshiharu Miyamoto, Koji Fujimoto, Jeon-Uk Lee, Ryuichiro Doi, Shigeki Arii, Masayuki Imamura

Cancer · 1998 · 156 citations · 23 references

DOIFull text

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Abstract

The results of the current study indicate that MMP-2 activation plays a significant role in tumor invasion and metastasis in pancreatic carcinoma.

References

23

A matrix metalloproteinase expressed on the surface of invasive tumour cells

Hiroshi Sato, Takahisa Takino, Yasunori Okada et al. · Nature · 1994 · 2.6K citations

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Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

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Metastatic potential correlates with enzymatic degradation of basement membrane collagen

Lance A. Liotta, Karl Tryggvason, Spiridione Garbisa et al. · Nature · 1980 · 1.8K citations

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Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

Alex Y. Strongin, Ivan E. Collier, G. A. Bannikov et al. · Journal of Biological Chemistry · 1995 · 1.6K citations · Full text

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

A Okada, J. P. Bellocq, N. Rouyer et al. · Proceedings of the National Academy of Sciences · 1995 · 500 citations · Full text