Concepedia

Phosphorylation of NLRC4 is critical for inflammasome activation

Yan Qu, Shahram Misaghi, Anita Izrael-Tomasevic, Kim Newton, Laurie L. Gilmour, Mohamed Lamkanfi, Salina Louie, Nobuhiko Kayagaki, Jinfeng Liu, László G. Kömüves,

Nature · 2012 · 314 citations · 20 references

DOI

Concepts

References

20

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations

, , +7

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Sanjeev Mariathasan, Kim Newton, Denise M. Monack et al. · Nature · 2004 · 1.8K citations

, , +14

NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder

Laetitia Agostini, Fabio Martinon, Kimberly Burns et al. · Immunity · 2004 · 1.7K citations · Full text

, , +15

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Vijay Rathinam, Zhaozhao Jiang, Stephen N. Waggoner et al. · Nature Immunology · 2010 · 1.3K citations · Full text

, , +16

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

Yue Zhao, Jieling Yang, Jianjin Shi et al. · Nature · 2011 · 1.3K citations

, , +16