Cooperativity in ligand binding: A new graphic analysis

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

Natural Sciences, Biophysics, Chemistry +9

A graphic method for the determination and presentation of binding parameters in a complex system

Hannah Rosenthal · Analytical Biochemistry · 1967 · 1.5K citations

Pharmacy, Biophysics, Chemistry +13

Insulin interactions with its receptors: Experimental evidence for negative cooperativity

Pierre De Meyts, Jesse Roth, David M. Neville et al. · Biochemical and Biophysical Research Communications · 1973 · 723 citations

Life Sciences, Biochemistry, Endocrinology +16

Properties of graphical representations of multiple classes of binding sites

Irving M. Klotz, Donald L. Hunston · Biochemistry · 1971 · 619 citations

Pharmacy, Computer Science, Analytical Chemistry +5

Heme Proteins

Jeffries Wyman · Advances in protein chemistry · 1948 · 512 citations