A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda

PubMed

PathologyCancer BiologyCancer ChemotherapyTumor BiologyOncology +15

Structure and properties of pharmacologically active polymers

Helmut Ringsdorf

Journal of Polymer Science Polymer Symposia

Macromolecular ChemistryEngineeringSmart PolymerResponsive PolymersPolymers +17

Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Cancer Research Campaign Phase I/II Committee.

P. Vasey, Stan B. Kaye, Rachel Morrison, +11

PubMed

PathologyPharmacotherapyMaximum Tolerated DoseMetronomic ChemotherapyTumor Biology +14

Encyclopedia of molecular cell biology and molecular medicine

Robert A. Meyers

Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes.

Kevin J. Harrington, S. Mohammadtaghi, Paul S. Uster, +4

PubMed

Tumor Liposome UptakeNuclear MedicineEngineeringOncologic ImagingGlioma +13

PEG−Doxorubicin Conjugates:  Influence of Polymer Structure on Drug Release, in Vitro Cytotoxicity, Biodistribution, and Antitumor Activity

Francesco M. Veronese, Oddone Schiavon, Gianfranco Pasut, +8

Bioconjugate Chemistry

Ethylene GlycolPharmaceutical ScienceAntitumor ActivityEngineeringPolymer-drug Conjugates +14

Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel

Jetske M. Meerum Terwogt, W.W. ten Bokkel Huinink, Jan H.M. Schellens, +7

Anti-Cancer Drugs

A Novel Biodegradable Gene Carrier Based on Polyphosphoester

Jun Wang, Hai‐Quan Mao, Kam W. Leong

Journal of the American Chemical Society

EngineeringAltmetric Attention ScoreMolecular BiologyBiodegradable PolymersGene Delivery +14

SMA–doxorubicin, a new polymeric micellar drug for effective targeting to solid tumours

Khaled Greish, Tomohiro Sawa, Jun Fang, +2

Journal of Controlled Release

Drug TargetingPolymer-drug ConjugateMedicinePharmacologyTumor Targeting +3

HPMA copolymer platinates as novel antitumour agents: in vitro properties, pharmacokinetics and antitumour activity in vivo

Elisabetta Gianasi, Mo Wasil, Evagoras G. Evagorou, +3

European Journal of Cancer

Hpma Copolymer PlatinatesMedicinePolymer-drug ConjugatePharmacologyNovel Antitumour Agents +7