Interaction of small molecule inhibitors of HIV-1 entry with CCR5

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

Krzysztof Palczewski, Takashi Kumasaka, Tetsuya Hori et al. · Science · 2000 · 5.6K citations

Life Sciences, Biochemistry, Biophysics +16

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

Rong Liu, William A. Paxton, Sunny Choe et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Infectious Diseases +13

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Michel Samson, Frédérick Libert, Benjamin J. Doranz et al. · Nature · 1996 · 2.9K citations

Life Sciences, Genetics, Molecular Genetics +11

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the <i>CKR5</i> Structural Gene

Michael Dean, Mary Carrington, Cheryl A. Winkler et al. · Science · 1996 · 2.5K citations

Life Sciences, Genetics, Molecular Genetics +8

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

Masanori Baba, Osamu Nishimura, Naoyuki Kanzaki et al. · Proceedings of the National Academy of Sciences · 1999 · 755 citations

Medicine, Immunology, Pharmacology +17