RETRACTED: 6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-κB factors

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

Gerald Cohen, Richard E. Heikkila, With the technical assistance of Dana MacNamee · Journal of Biological Chemistry · 1974 · 896 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Distinct Mechanisms Underlie Neurotoxin-Mediated Cell Death in Cultured Dopaminergic Neurons

Julie Lotharius, Laura L. Dugan, Karen L. O’Malley · Journal of Neuroscience · 1999 · 405 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine

Yelena Glinka, Moussa B. H. Youdim · European Journal of Pharmacology Environmental Toxicology and Pharmacology · 1995 · 284 citations

Life Sciences, Neuroscience, Pharmacology +12

Two distinct mechanisms are involved in 6-hydroxydopamine- and MPP+-induced dopaminergic neuronal cell death: Role of caspases, ROS, and JNK

Won‐Seok Choi, So-Young Yoon, Tae Hwan Oh et al. · Journal of Neuroscience Research · 1999 · 261 citations

Life Sciences, Neurobiology, Neuroscience +17

Dopamine, 6-hydroxydopamine, iron, and dioxygen — their mutual interactions and possible implication in the development of Parkinson's disease

Wolfgang Linert, Erwin Herlinger, Reginald F. Jameson et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 1996 · 238 citations

Life Sciences, Neurobiology, Neuroscience +14