Experimental ischemic heart disease—Effects of synthetic thromboxane A2

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Mats Hámberg, Jan Olof Svensson, B Samuelsson · Proceedings of the National Academy of Sciences · 1975 · 3.1K citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

Mats Hámberg, Jan Svensson, Toshio Wakabayashi et al. · Proceedings of the National Academy of Sciences · 1974 · 998 citations · Full text

Medicine, Biochemistry, Biochemical Pharmacology +10

Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

Tsumoru Miyamoto, N Ogino, Shogo Yamamoto et al. · Journal of Biological Chemistry · 1976 · 668 citations · Full text

Life Sciences, Biochemistry, Enzymology +11

Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides

Philip Needleman, Salvador Moncada, S Bunting et al. · Nature · 1976 · 526 citations

Medicine, Biochemistry, Pharmacology +16

Coronary Arterial Smooth Muscle Contraction by a Substance Released from Platelets: Evidence That It Is Thromboxane A ₂

Earl F. Ellis, O Oelz, N A Payne et al. · Science · 1976 · 498 citations

Medicine, Biochemistry, Cardiology +15