NF-κB activated by ER calcium release inhibits Aβ-mediated expression of CHOP protein: Enhancement by AD-linked mutant presenilin 1

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

Ephrat Levy‐Lahad, Wilma Wasco, Parvoneh Poorkaj et al. · Science · 1995 · 2.6K citations

Alzheimer's Disease, Genetic Disorder, Genetics +12

Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

Karen D. McCullough, Jennifer L. Martindale, Lars‐Oliver Klotz et al. · Molecular and Cellular Biology · 2001 · 1.9K citations · Full text

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

Albert J. Fornace, Daniel W. Nebert, M. Christine Hollander et al. · Molecular and Cellular Biology · 1989 · 689 citations · Full text

Dna Damage, Genetics, Cell Proliferation +19

Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153)

Xiao-Zhong Wang, Beth Lawson, Joseph W. Brewer et al. · Molecular and Cellular Biology · 1996 · 672 citations · Full text

Reductive Stress, Protein Function, Signal Transduction +15

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

Bin Cheng, Sylvia Christakos, Mark P. Mattson · Neuron · 1994 · 668 citations

Inflammation, Energy Homeostasis, Neurophysiology +12