Concepedia

Mitochondrial complex I inhibitors, acetogenins, induce HepG2 cell death through the induction of the complete apoptotic mitochondrial pathway

Nuria de Pedro, Bastien Cautain, Ángeles Melguizo, Francisca Vicente, Olga Genilloud, Fernando Peláez, José R. Tormo

Journal of Bioenergetics and Biomembranes · 2012 · 43 citations · 46 references

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46

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Ranjita Betarbet, Todd Sherer, Gillian M. MacKenzie et al. · Nature Neuroscience · 2000 · 3.7K citations

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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

Naoufal Zamzami, Philippe Marchetti, Maria Castedo et al. · The Journal of Experimental Medicine · 1995 · 1.6K citations · Full text

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Mitochondrial Complex I Inhibitor Rotenone Induces Apoptosis through Enhancing Mitochondrial Reactive Oxygen Species Production

Nianyu Li, Kathy Ragheb, Gretchen Lawler et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

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Mitochondrial control of nuclear apoptosis.

Naoufal Zamzami, Santos A. Susín, Philippe Marchetti et al. · The Journal of Experimental Medicine · 1996 · 1.4K citations · Full text

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