ALS/FTLD-linked TDP-43 regulates neurite morphology and cell survival in differentiated neurons

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.6K citations

Life Sciences, Neurology, Neuroscience +14

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama et al. · Biochemical and Biophysical Research Communications · 2006 · 2.8K citations

Life Sciences, Neurology, Neuroscience +11

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

S.-H.I. Ou, F Wu, David Harrich et al. · Journal of Virology · 1995 · 760 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

Vivianna M. Van Deerlin, James B. Leverenz, Lynn M. Bekris et al. · The Lancet Neurology · 2008 · 720 citations

Life Sciences, Neurology, Neuroscience +15

Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation

Matthew J. Winton, Lionel M. Igaz, Margaret Wong et al. · Journal of Biological Chemistry · 2008 · 670 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17