Concepedia

Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

Fa Liu, Jung‐Eun Park, Wen‐Jian Qian, Dan Lim, Martin Gräber, Thorsten Berg, Michael B. Yaffe, Kyung S. Lee, Terrence R. Burke

Nature Chemical Biology · 2011 · 109 citations · 30 references

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30

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

Ji Luo, Michael J. Emanuele, Danan Li et al. · Cell · 2009 · 1K citations

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The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain

Andrew E. H. Elia, Peter Rellos, L.F. Haire et al. · Cell · 2003 · 769 citations · Full text

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Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates

Andrew E. H. Elia, Lewis C. Cantley, Michael B. Yaffe · Science · 2003 · 683 citations

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The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1

Péter Lénárt, Mark Petronczki, Martin Steegmaier et al. · Current Biology · 2007 · 677 citations · Full text

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ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent

Kiranmai Gumireddy, M. V. Ramana Reddy, Stephen C. Cosenza et al. · Cancer Cell · 2005 · 368 citations · Full text

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