β-Amyloid precursor protein (βAPP) as a marker for axonal injury after head injury

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

Life Sciences, Molecular Biology, Neuroscience +14

Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

Peter Seubert, Carmen Vigo‐Pelfrey, Fred Esch et al. · Nature · 1992 · 1.7K citations

Life Sciences, Biochemistry, Neuroscience +13

Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing

Mikio Shoji, Todd E. Golde, Jorge Ghiso et al. · Science · 1992 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +14

Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

Christian Haass, Edward H. Koo, Angela Mellon et al. · Nature · 1992 · 897 citations

Life Sciences, Biochemistry, Cell Biology +16

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

Edward H. Koo, Sangram S. Sisodia, David R. Archer et al. · Proceedings of the National Academy of Sciences · 1990 · 730 citations

Life Sciences, Neurobiology, Neuroscience +17