Concepedia

Resistance-modifying agents. Part 7: 2,6-disubstituted-4,8-dibenzylaminopyrimido[5,4-d]pyrimidines that inhibit nucleoside transport in the presence of α1-acid glycoprotein (AGP)

Hannah C Barlow, Karen J. Bowman, Nicola J. Curtin, A H Calvert, Bernard T. Golding, Bing Huang, Peter J. Loughlin, David R. Newell, Peter G. Smith, Roger J. Griffin

Bioorganic & Medicinal Chemistry Letters · 2000 · 10 citations · 9 references

DOI

Concepts

References

9

Modulation of anti-metabolite effects

Ann L. Jackman, Gordon A. Taylor, A H Calvert et al. · Biochemical Pharmacology · 1984 · 97 citations

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Relation between raised concentrations of fucose, sialic acid, and acute phase proteins in serum from patients with cancer: choosing suitable serum glycoprotein markers.

G. A. Turner, A. W. Skillen, P K Buamah et al. · Journal of Clinical Pathology · 1985 · 75 citations · Full text

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Nucleoside Transport Inhibitors: Structure-Activity Relationships and Potential Therapeutic Applications

John K. Buolamwini · Current Medicinal Chemistry · 1997 · 54 citations

, , +13

Phase I trial of dipyridamole with 5-fluorouracil and folinic acid.

G. Thomas Budd, A. P. Jayaraj, D Grabowski et al. · PubMed · 1990 · 32 citations

, , +11

Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced α 1-acid glycoprotein binding

Nicola J. Curtin, Karen J. Bowman, RN Turner et al. · British Journal of Cancer · 1999 · 19 citations · Full text

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