Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science · 2007 · 10.3K citations

Life Sciences, Cell Biology, Developmental Biology +17

Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells

Jonathan S. Draper, Kath Smith, Paul J. Gokhale et al. · Nature Biotechnology · 2003 · 1K citations

Life Sciences, Genetics, Molecular Genetics +10

Risks of leukaemia and solid tumours in individuals with Down's syndrome

Henrik Hasle, Inge Clemmensen, Margareta Mikkelsen · The Lancet · 2000 · 896 citations

Life Sciences, Genetics, Oncology +12

Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

Dong-Chuan Guo, Hariyadarshi Pannu, Van Tran‐Fadulu et al. · Nature Genetics · 2007 · 846 citations

Medicine, Cardiology, Surgery +14

Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

Yoav Mayshar, Uri Ben‐David, Neta Lavon et al. · Cell stem cell · 2010 · 768 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13