Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections

Aneurysm Syndromes Caused by Mutations in the TGF-β Receptor

Bart Loeys, Ulrike Schwarze, Tammy M. Holm et al. · New England Journal of Medicine · 2006 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

Anja A. T. Geisterfer-Lowrance, Susan Kass, G Tanigawa et al. · Cell · 1990 · 1.4K citations

Medicine, Genetics, Molecular Genetics +10

At least six different actins are expressed in a higher mammal: An analysis based on the amino acid sequence of the amino-terminal tryptic peptide

Joël Vandekerckhove, Klaus Weber · Journal of Molecular Biology · 1978 · 741 citations

Life Sciences, Biochemistry, Molecular Biology +6

Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus

Li‐Min Zhu, Roger Vranckx, Philippe Khau Van Kien et al. · Nature Genetics · 2006 · 614 citations

Medicine, Cardiology, Genetics +14

The Crystal Structure of Uncomplexed Actin in the ADP State

Ludovic R. Otterbein, Philip Graceffa, Roberto Domínguez · Science · 2001 · 527 citations

Life Sciences, Biochemistry, Biophysics +15