Concepedia

Publication | Open Access

Analysis of Fecal DNA Methylation to Detect Gastrointestinal Neoplasia

DOIFull Paper Access

128

Citations

42

References

2009

Year

Takeshi Nagasaka, Noriaki Tanaka, Harry M. Cullings, Dong-Sheng Sun, Hiromi Sasamoto, T Uchida, Minoru Koi, Naoshi Nishida, Yoshio Naomoto, C. Richard Boland,
JNCI Journal of the National Cancer Institute

Abstract

Methylation of the RASSF2 and SFRP2 promoters in fecal DNA is associated with the presence of gastrointestinal tumors relative to non-neoplastic conditions. Our novel fecal DNA methylation assay provides a possible means to noninvasively screen not only for colorectal tumors but also for gastric tumors.

References

YearCitations

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