The role of Akt1 in terminal stages of endochondral bone formation: Angiogenesis and ossification

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho, James Mu, Jason K. Kim et al. · Science · 2001 · 1.8K citations

Life Sciences, Biochemistry, Molecular Biology +17

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

Kenn Holmbeck, Paolo Bianco, John J. Caterina et al. · Cell · 1999 · 1.3K citations · Full text

Medicine, Pathobiology, Pathology +12

Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice

Han Cho, Joanne L. Thorvaldsen, Qingwei Chu et al. · Journal of Biological Chemistry · 2001 · 963 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Growth retardation and increased apoptosis in mice with homozygous disruption of the <i>akt1</i> gene

William S. Chen, Pei-Zhang Xu, Kathrin Gottlob et al. · Genes & Development · 2001 · 922 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2

Xiao-ding Peng, Pei-Zhang Xu, Mei-Ling Chen et al. · Genes & Development · 2003 · 826 citations · Full text

Medicine, Developmental Biology, Genetics +17