Involvement of Jak2 tyrosine phosphorylation in Bcr–Abl transformation

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

Brian Druker, Shu Tamura, Elisabeth Buchdunger et al. · Nature Medicine · 1996 · 3.6K citations

Signal Transduction, Cell Regulation, Abl Tyrosine Kinase +10

Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

Evan Parganas, Demin Wang, Dimitrios J. Stravopodis et al. · Cell · 1998 · 1.2K citations · Full text

Inflammation, Cytokine, Signal Transduction +10

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

Zhou Songyang, Kermit L. Carraway, Michael J. Eck et al. · Nature · 1995 · 926 citations

Signal Transduction, Engineering, Signaling Pathway +8

Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis

Hans Neubauer, Ana Cumano, Mathias Müller et al. · Cell · 1998 · 907 citations · Full text

Developmental Biology, Cell Division, Receptor Tyrosine Kinase +5

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

Ann Marie Pendergast, Lawrence A. Quilliam, Larry D. Cripe et al. · Cell · 1993 · 656 citations

Signal Transduction, Signaling Pathway, Oncogenic Agent +9