International Journal of Environmental Health Research · 2013 · 22 citations · 23 references
PharmacyEnvironmental SciencesToxicologyEnvironmental HealthEnvironmental ToxicologyOccupational ToxicologyExposure AssessmentSecondhand Smoke ExposureTobacco UseAdult Secondhand Smoke ExposureBar LevelsCotinine Exposure AssessmentExposure To Secondhand SmokeExposure-time RelationshipHealth Effects Of SmokeSecondhand Smoke BiomarkersSimulated Environments
We assessed the acute effects of a 1-h exposure to second-hand smoke (SHS) on complete blood count (CBC) markers in a controlled simulated bar/restaurant environment. Nineteen adult never-smokers completed a 1-h .exposure to SHS at bar/restaurant levels, and a 1-h exposure to normal room air. Blood samples were collected at the baseline at 30 min during each exposure, and at 0, 0.5, 1, 2, 3, and 4 h after each exposure. The values of white blood cells (WBC) at 1 h (p = 0.010), 3 h (p = 0.040), and 4 h (p = 0.008) following SHS were significantly increased compared with the baseline values. Also, there was a positive association between the WBC and cotinine levels (r = 0.28, p = 0.007). A 1-h exposure to SHS at bar/restaurant levels significantly increased the WBC for at least 4 h following the exposure time. This effect of SHS on WBC has dose-response characteristics and should be considered to prescribing CBC.
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