Neuroleptic activity of the neuropeptide β-LPH62–77 ([Des-Tyr1]γ-endorphin; DTγE)

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness

Floyd E. Bloom, David J. Segal, Nicholas Ling et al. · Science · 1976 · 812 citations

Medicine, Neuroscience, Pharmacology +17

C fragment of lipotropin has a high affinity for brain opiate receptors

A.F. Bradbury, D.G. Smyth, Christopher R. Snell et al. · Nature · 1976 · 486 citations

Life Sciences, Endocrinology, Neuroscience +5

Retention of a passive avoidance response as a function of the intensity and duration of electric shock

Robert Ader, J.A.W.M. Weijnen, P. Moleman · Psychonomic Science · 1972 · 431 citations · Full text

Social Sciences, Behavioral Sciences, Psychology +8

The C-Fragment of β-Lipotropin: An Endogenous Neuroleptic or Antipsychotogen?

Yasuko F. Jacquet, Neville Marks · Science · 1976 · 426 citations

Life Sciences, Neuroscience, Pharmacology +17