Concepedia

Evidence that γ-secretase mediates oxidative stress-induced β-secretase expression in Alzheimer's disease

Dong‐Gyu Jo, Thiruma V. Arumugam, Ha‐Na Woo, Jong Sung Park, Sung‐Chun Tang, Mohamed R. Mughal, Dong‐Hoon Hyun, Jun Hyung Park, Yun‐Hyung Choi, A‐Ryeong Gwon,

Neurobiology of Aging · 2008 · 105 citations · 25 references

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References

25

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

, , +12

BACE1 is the major β-secretase for generation of Aβ peptides by neurons

Huaibin Cai, Yanshu Wang, Diane B. McCarthy et al. · Nature Neuroscience · 2001 · 1.1K citations

, , +14

Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis

Domenico Praticò, Kunihiro Uryu, Susan Leight et al. · Journal of Neuroscience · 2001 · 780 citations · Full text

, , +17

Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease.

PubMed · 1997 · 750 citations

, , +17

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating <i>BACE1</i> gene expression

Xiulian Sun, Guiqiong He, Hong Qing et al. · Proceedings of the National Academy of Sciences · 2006 · 601 citations

, , +17