Concepedia

Synthesis and evaluation of N-acyl-substituted 1,2-benzisothiazol-3-one derivatives as caspase-3 inhibitors

Zheng-Hui Li, Yang Pan, Weilong Zhong, Yunpeng Zhu, Yongle Zhao, Lixin Li, Wei Liu, Honggang Zhou, Cheng Yang

Bioorganic & Medicinal Chemistry · 2014 · 11 citations · 18 references

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18

Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

Eswaran Devarajan, Ayşegül A. Şahin, Jack S. Chen et al. · Oncogene · 2002 · 465 citations

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Design, Synthesis, and Biological Characterization of a Caspase 3/7 Selective Isatin Labeled with 2-[<sup>18</sup>F]fluoroethylazide

Graham Smith, Matthias Glaser, Meg Perumal et al. · Journal of Medicinal Chemistry · 2008 · 131 citations · Full text

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Design, Synthesis, and Biological Evaluation of Isoquinoline-1,3,4-trione Derivatives as Potent Caspase-3 Inhibitors

Yahui Zhang, Hua-jie Zhang, Dazhi Liu et al. · Journal of Medicinal Chemistry · 2006 · 126 citations · Full text

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Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis

Dong Zhou, Wenhua Chu, Justin M. Rothfuss et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 104 citations · Full text

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<i>N</i>-Benzylisatin Sulfonamide Analogues as Potent Caspase-3 Inhibitors:  Synthesis, in Vitro Activity, and Molecular Modeling Studies

Wenhua Chu, Jun Zhang, Chenbo Zeng et al. · Journal of Medicinal Chemistry · 2005 · 104 citations · Full text

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