Advanced Glycation End Products Are Direct Modulators of β-Cell Function - Concepedia

Concepedia

Publication | Open Access

Advanced Glycation End Products Are Direct Modulators of β-Cell Function

DOI Full Paper Access

151

Citations

49

References

2011

Year

Melinda T. Coughlan, Felicia Y. T. Yap, David Tong, Sofianos Andrikopoulos, Anna Gasser, Vicki Thallas‐Bonke, Diane E. Webster, Jun‐ichi Miyazaki, Thomas W. H. Kay, Robyn M. Slattery,

Abstract

These findings demonstrate that AGEs directly cause insulin secretory defects, most likely by impairing mitochondrial function, which may contribute to the development of T1D.

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