Concepedia

Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest

Gábor Szabó, Volker Buhmann, Terézia B. Andrási, Nicole Stumpf, Susanne Bährle, Violetta Kékesi, Siegfried Hagl, Csaba Szabó, Alexander Juhász‐Nagy

Journal of Thoracic and Cardiovascular Surgery · 2003 · 20 citations · 33 references

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References

33

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.

Csaba Szabó, Basilia Zingarelli, Michael O′Connor et al. · Proceedings of the National Academy of Sciences · 1996 · 624 citations · Full text

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Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

Francisco García Soriano, László Virág, Prakash G. Jagtap et al. · Nature Medicine · 2001 · 603 citations · Full text

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Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

Ingrid U. Schraufstätter, Daniel B. Hinshaw, Paul A. Hyslop et al. · Journal of Clinical Investigation · 1986 · 513 citations · Full text

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In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

Andrew S. Weyrich, X Y, David J. Lefer et al. · Journal of Clinical Investigation · 1993 · 452 citations · Full text

, , +14

Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.

Csaba Szabó, Salvatore Cuzzocrea, Basilia Zingarelli et al. · Journal of Clinical Investigation · 1997 · 358 citations · Full text

, , +15