MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis

Cortical demyelination and diffuse white matter injury in multiple sclerosis

Alexandra Kutzelnigg, Claudia F. Lucchinetti, Christine Stadelmann et al. · Brain · 2005 · 1.8K citations

Medicine, Neurology, Pathology +17

Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions

John W. Peterson, Ansi Chang, Bruce D. Trapp · Annals of Neurology · 2001 · 1.4K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Activation of microglial cells by β-amyloid protein and interferon-γ

Lucia Meda, Marco A. Cassatella, Györgyi I. Szendrei et al. · Nature · 1995 · 1.3K citations

Life Sciences, Immunology, Neuroscience +14

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

Stefano Pluchino, Angelo Quattrini, Elena Brambilla et al. · Nature · 2003 · 1.1K citations

Life Sciences, Neurology, Neuroscience +17

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

Seija Lehnardt, Leon J. Massillon, Pamela L. Follett et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17