Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Axel T. Brünger, Paul D. Adams, G. Marius Clore et al. · Acta Crystallographica Section D Biological Crystallography · 1998 · 15.8K citations

Natural Sciences, Biophysics, Chemistry +17

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

Life Sciences, Biochemistry, Biomolecular Modeling +16

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Andreas Hörlein, Anders M. Näär, Thorsten Heinzel et al. · Nature · 1995 · 2.1K citations

Life Sciences, Endocrinology, Molecular Biology +16

The drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily

Michael R. Koelle, William S. Talbot, William A. Segraves et al. · Cell · 1991 · 986 citations

Life Sciences, Entomology, Genetics +11

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes

Tso‐Pang Yao, Barry M. Forman, Zeyu Jiang et al. · Nature · 1993 · 949 citations

Life Sciences, Genetics, Molecular Biology +9