Inside Alzheimer brain with CLARITY: senile plaques, neurofibrillary tangles and axons in 3-D

Structural and molecular interrogation of intact biological systems

Kwanghun Chung, Jenelle L. Wallace, Sung‐Yon Kim et al. · Nature · 2013 · 2.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

Etsuo A. Susaki, Kazuki Tainaka, Dimitri Perrin et al. · Cell · 2014 · 1.4K citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain

Hiroshi Hama, Hiroshi Kurokawa, Hiroyuki Kawano et al. · Nature Neuroscience · 2011 · 1.2K citations

Natural Sciences, Neurobiology, Neuroscience +14

Three-dimensional imaging of solvent-cleared organs using 3DISCO

Ali Ertürk, Klaus Becker, Nina Jährling et al. · Nature Protocols · 2012 · 1K citations

Computing, Biomedical Engineering, Radiology +14

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

Melanie Meyer‐Luehmann, Tara L. Spires‐Jones, Claudia Prada et al. · Nature · 2008 · 993 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17