Concepedia

LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice

Rong Li, Judy P. Doherty, Juliana Antonipillai, Sheng Chen, Mark Devlin, Kathryn Visser, Jonathan B. Baell, Ian P. Street, Robin L. Anderson, Ora Bernard

Clinical & Experimental Metastasis · 2012 · 45 citations · 35 references

DOI

Concepts

References

35

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

Midori Maekawa, Toshimasa Ishizaki, Shuken Boku et al. · Science · 1999 · 1.6K citations

, , +17

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

Silvia Arber, Freda A. Barbayannis, Hartwig Hanser et al. · Nature · 1998 · 1.4K citations

, , +12

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

Neng Yang, Osamu Higuchi, Kazumasa Ohashi et al. · Nature · 1998 · 1.3K citations

, , +14

Regulation of the actin cytoskeleton in cancer cell migration and invasion

Hideki Yamaguchi, John S. Condeelis · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2006 · 1.2K citations · Full text

, , +14

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

David C. Edwards, Luraynne C. Sanders, Gary Bokoch et al. · Nature Cell Biology · 1999 · 1.1K citations

, , +14