Concepedia

USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation

Yang Yu, R-F Mao, X-J Tan, G-F Xu, H Zhang, X-B Lu, S-B Fu, Jianhua Yang

Cell Death and Differentiation · 2011 · 150 citations · 32 references

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32

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

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Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Li Deng, Chen Wang, Erika Spencer et al. · Cell · 2000 · 1.9K citations · Full text

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The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

Jun Ninomiya‐Tsuji, Kazuya Kishimoto, Atsushi Hiyama et al. · Nature · 1999 · 1.2K citations

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TNF-Dependent Recruitment of the Protein Kinase RIP to the TNF Receptor-1 Signaling Complex

Hailing Hsu, Jianing Huang, Hong-Bing Shu et al. · Immunity · 1996 · 1.2K citations · Full text

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cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

Mathieu J.M. Bertrand, Snezana Milutinovic, Kathleen M. Dickson et al. · Molecular Cell · 2008 · 1.1K citations

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