Concepedia
Bioorganic & Medicinal Chemistry Letters · 2006 · 14 citations · 11 references
Life SciencesInfectious DiseasesMolecular VirologyPlant VirologyVirologyAntiviral ImmunityMucosal PermeabilityPlant VirusesViral InfectionsVirus-host InteractionsCaco-2 Cell AssayIntestinal Barrier PermeabilityIntestinal Permeability ModelingViral Fruit DiseasesVirus Diseases
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Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations
Pharmacy, Pharmacokinetics, Pharmacology +16
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
Inka Leier, Gabriele Jedlitschky, Ulrike Buchholz et al. · Journal of Biological Chemistry · 1994 · 856 citations · Full text
Medicine, Biochemistry, Pharmacology +14
Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption
David E. Clark · Journal of Pharmaceutical Sciences · 1999 · 618 citations
Pharmacy, Biophysics, Chemical Engineering +15
Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat
J. R. Pappenheimer · The Journal of Membrane Biology · 1987 · 525 citations
Life Sciences, Cell Biology, Physiology +16
Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight
Gian Camenisch, Jochem Alsenz, H. Van De Waterbeemd et al. · European Journal of Pharmaceutical Sciences · 1998 · 343 citations
Pharmacy, Biophysics, Pharmacology +14