Concepedia

Intestinal Permeability Modeling

Intestinal Permeability Modeling is a computational or mathematical framework that characterizes the rate and mechanisms of solute transport across the intestinal epithelium, distinguishing it from broader gastrointestinal models by focusing specifically on membrane barrier function and absorptive capacity in the context of bioavailability prediction.

197

Publications

15.6K

Citations

797

Authors

280

Institutions

Publications per year

2017–2026

57

Parents

Publications

197

A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

Antoine Daina, Vincent Zoete · ChemMedChem · 2016 · 2.4K citations · Full text

, , +17

In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth

Shiyin Yee · Pharmaceutical Research · 1997 · 1K citations

, , +13

Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption

David E. Clark · Journal of Pharmaceutical Sciences · 1999 · 618 citations

, , +15

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

Shinji Yamashita, Tomoyuki Furubayashi, Makoto Kataoka et al. · European Journal of Pharmaceutical Sciences · 2000 · 565 citations

, , +14

Correlation of Human Jejunal Permeability (in Vivo) of Drugs with Experimentally and Theoretically Derived Parameters. A Multivariate Data Analysis Approach

Susanne Winiwarter, Nicholas M. Bonham, Fredrik Ax et al. · Journal of Medicinal Chemistry · 1998 · 452 citations

, , +17

1–5 of 197

Authors

797

  1. AD
    Arik Dahan

    Ben-Gurion University of the Negev, Israel

    10 publications · 833 citations

    10

    h-index

  2. HL
    Hans Lennernäs

    Uppsala University, Sweden

    7 publications · 686 citations

    7

    h-index

  3. GL
    Gordon L. Amidon

    University of Michigan, United States

    6 publications · 736 citations

    6

    h-index

  4. BS
    Bruno Sarmento

    Universidade do Porto, Portugal

    6 publications · 529 citations

    6

    h-index

  5. CT
    Christer Tannergren

    AstraZeneca (Sweden), Sweden

    5 publications · 395 citations

    5

    h-index

1–5 of 797

Institutions

280

  1. Ben-Gurion University of the Negev

    Beersheba, Israel

    9 h-index

    35 publications

    1.9K citations

  2. Uppsala University

    Uppsala, Sweden

    9 h-index

    37 publications

    5.5K citations

  3. AstraZeneca (Sweden)

    Södertälje, Sweden

    7 h-index

    25 publications

    3.6K citations

  4. Universidade do Porto

    Porto, Portugal

    6 h-index

    16 publications

    1K citations

  5. Universitat de València

    Valencia, Spain

    6 h-index

    11 publications

    913 citations

  6. Universidad Central "Marta Abreu" de las Villas (UCLV)

    Santa Clara, Cuba

    6 h-index

    13 publications

    620 citations

  7. Universitat de Miguel Hernández d'Elx

    Elche, Spain

    6 h-index

    22 publications

    1.7K citations

  8. University of Michigan

    Ann Arbor, United States

    5 h-index

    22 publications

    2K citations

1–8 of 280

Venues

  1. International Journal of Pharmaceutics

    12 publications · 805 citations

    12

    h-index

  2. Pharmaceutical Research

    11 publications · 1.8K citations

    11

    h-index

  3. European Journal of Pharmaceutical Sciences

    10 publications · 1.1K citations

    10

    h-index

  4. Journal of Pharmaceutical Sciences

    10 publications · 988 citations

    10

    h-index

  5. Molecular Pharmaceutics

    8 publications · 681 citations

    8

    h-index

1–5