H. Van De Waterbeemd

Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight

Gian Camenisch, Jochem Alsenz, H. Van De Waterbeemd et al. · European Journal of Pharmaceutical Sciences · 1998 · 343 citations

Pharmacy, Biophysics, Pharmacology +14

Estimation of Caco‐2 Cell Permeability using Calculated Molecular Descriptors

H. Van De Waterbeemd, Gian Camenisch, Gerd Folkers et al. · Quantitative Structure-Activity Relationships · 1996 · 202 citations

Natural Sciences, Biophysics, Cell Biophysics +16

Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors

Kurt Hilpert, Jean Ackermann, David W. Banner et al. · Journal of Medicinal Chemistry · 1994 · 190 citations · Full text

Medicine, Chemistry, Pharmacology +13

Hydrogen-Bonding Capacity and Brain Penetration

H. Van De Waterbeemd, Manfred Kansy · CHIMIA International Journal for Chemistry · 1992 · 188 citations · Full text

Pharmacy, Chemistry, Pharmacology +14

Substructure and whole molecule approaches for calculating log P

Raimund Mannhold, H. Van De Waterbeemd · Journal of Computer-Aided Molecular Design · 2001 · 178 citations

Natural Sciences, Chemistry, Computational Chemistry +13