The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Jeffery D. Molkentin, Jianrong Lu, Christopher L. Antos et al. · Cell · 1998 · 2.6K citations · Full text

Cardiac Muscle, Transcriptional Regulation, Cardiomyopathy +8

TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao, Xin Ye, Jindan Yu et al. · Genes & Development · 2008 · 2.5K citations · Full text

Hippo Pathway, Developmental Biology, Signaling Pathway +10

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

Todd R. Heallen, Min Zhang, Jun Wang et al. · Science · 2011 · 1.1K citations

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

Dawang Zhou, Claudius Conrad, Fan Xia et al. · Cancer Cell · 2009 · 927 citations · Full text

Tumor Biology, Hepatology, Medicine +9

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

Eiki Takimoto, Hunter C. Champion, Manxiang Li et al. · Nature Medicine · 2005 · 894 citations

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +9