A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Jeffery D. Molkentin, Jianrong Lu, Christopher L. Antos, +5

Cell

Cardiac MuscleTranscriptional RegulationCardiomyopathyMolecular PhysiologySignal Transduction +6

TEAD mediates YAP-dependent gene induction and growth control

Bin Zhao, Xin Ye, Jindan Yu, +9

Genes & Development

Hippo PathwayDevelopmental BiologySignaling PathwayYap Transcription CoactivatorGenetics +8

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

Todd R. Heallen, Min Zhang, Jun Wang, +4

Science

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

Dawang Zhou, Claudius Conrad, Fan Xia, +8

Cancer Cell

Tumor BiologyHepatologyMedicineLiver PhysiologyPathology +7

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

Eiki Takimoto, Hunter C. Champion, Manxiang Li, +7

Nature Medicine

Cardiac MuscleCardiomyopathyMolecular PhysiologyCardiovascular DiseaseBiochemistry +7

Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways

Michael A. Crackower, Gavin Y. Oudit, I. Kozieradzki, +20

Cell

MechanobiologyCardiac MuscleCardiomyopathyCell SizeMolecular Physiology +9

YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

Alexander von Gise, Zhiqiang Lin, Karin Schlegelmilch, +8

Proceedings of the National Academy of Sciences

Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5

Rick B. Vega, Brooke C. Harrison, Eric S. Meadows, +4

Molecular and Cellular Biology

Cardiac MuscleHeart FailureCardiovascular FunctionCell RegulationPkc Signaling +19

CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy

Johannes Backs

Journal of Clinical Investigation

Cardiac MuscleDeacetylase 4Molecular RegulationMolecular BiologyCam Kinase Ii +19

Akt/Protein Kinase B Promotes Organ Growth in Transgenic Mice

Tetsuo Shioi, Julie R. McMullen, Peter M. Kang, +5

Molecular and Cellular Biology

Cardiac MuscleInsulin ReceptorTransgenic MiceCellular PhysiologyInsulin Signaling +14