Concepedia

Antifungal rapamycin analogues with reduced immunosuppressive activity

Daniel A. Dickman, Hong Ding, Qun Li, Angela M. Nilius, Darlene Balli, Stephen J. Ballaron, James M. Trevillyan, Morey L. Smith, Louis S. Seif, Ki H. Kim,

Bioorganic & Medicinal Chemistry Letters · 2000 · 18 citations · 14 references

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14

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

Joseph Heitman, N. Rao Movva, Michael N. Hall · Science · 1991 · 2K citations

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Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.

Claude Vézina, ALICIA KUDELSKI, Suren N. Sehgal · The Journal of Antibiotics · 1975 · 1.7K citations · Full text

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Rapamycin blocks the phosphorylation of 4E‐BP1 and inhibits cap‐dependent initiation of translation.

Laura Beretta, Anne‐Claude Gingras, Yuri V. Svitkin et al. · The EMBO Journal · 1996 · 673 citations · Full text

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Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

George K. Abruzzo, Amy Flattery, Christopher Gill et al. · Antimicrobial Agents and Chemotherapy · 1997 · 245 citations · Full text

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A new triazole, voriconazole (UK-109,496), blocks sterol biosynthesis in Candida albicans and Candida krusei

Homayoon Sanati, Paul H. Belanger, Rutilio A. Fratti et al. · Antimicrobial Agents and Chemotherapy · 1997 · 218 citations · Full text

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