Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor γ for monocyte recruitment and endothelial regeneration

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

Transcriptional Regulation, Cell Signaling, Physiology +10

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

Inflammation, Macrophage Biology, Cell Autophagy +11

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Landin Boring, Jennifa Gosling, Michael D. Cleary et al. · Nature · 1998 · 2K citations

Inflammation, Ccr2−/− Mice, Vascular Disease +13

Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

László Nagy, Peter Tontonoz, Jacqueline G. Alvarez et al. · Cell · 1998 · 1.9K citations · Full text

Inflammation, Ligand Activation, Signal Transduction +10