Concepedia

Synthesis of Quinoline-2-thiones via Tandem Indium(III)-Promoted Friedel−Crafts Alkenylation−Cyclization of 2-Alkynylphenyl Isothiocyanates

Takashi Otani, Shinichi Kunimatsu, Hiroshi Nihei, Yuko Abe, Takao Saito

Organic Letters · 2007 · 46 citations · 27 references

DOI

Concepts

Abstract

A new approach to the synthesis of 4-aryl- or 4-arylthioquinoline-2-thiones via indium(III) reagent-mediated tandem Friedel-Crafts alkenylation-cyclization of 2-alkynylphenyl isothiocyanates is described.

References

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