Concepedia

Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

Yuanyuan Du, Jinlin Wang, Jun Jia, Nan Song, Chengang Xiang, Jun Xu, Zhiyuan Hou, Xiaohua Su, Bei Liu, Tao Jiang,

Cell stem cell · 2014 · 323 citations · 8 references

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Concepts

References

8

Vascularized and functional human liver from an iPSC-derived organ bud transplant

Takanori Takebe, Keisuke Sekine, Masahiro Enomura et al. · Nature · 2013 · 2.1K citations

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Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

Pengyu Huang, Zhiying He, Shuyi Ji et al. · Nature · 2011 · 860 citations

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Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

Sayaka Sekiya, Atsushi Suzuki · Nature · 2011 · 838 citations

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Directed differentiation of human embryonic stem cells into functional hepatic cells†

Jun Cai, Yang Zhao, Yanxia Liu et al. · Hepatology · 2007 · 627 citations · Full text

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Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.

Paweł Baranczewski, Andrzej Stańczak, Kathrin Sundberg et al. · PubMed · 2007 · 290 citations

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