Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

Yuanyuan Du, Jinlin Wang, Jun Jia, +16

Cell stem cell

Systems BiologyHepatologyMetabolic ReprogrammingLiver PhysiologyMetabolic Functions +10

Long-term functional maintenance of primary human hepatocytes in vitro

Chengang Xiang, Yuanyuan Du, Gaofan Meng, +24

Science

Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury

Weijian Yao, Ying Chen, Zehua Li, +13

Advanced Science

Generation of Naive Induced Pluripotent Stem Cells from Rhesus Monkey Fibroblasts

Riguo Fang, Kang Liu, Yang Zhao, +12

Cell stem cell

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellDevelopmental BiologyRhesus Monkey Fibroblasts +10

A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts

Bingqing Xie, Da Sun, Yuanyuan Du, +23

Cell Research

TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity

Xing Tian, Huijun Dong, Xinyuan Lai, +14

Antiviral Research

Viral ReplicationMolecular VirologyViral PersistencePathogenesisViral Pathogenesis +5

Human Amniotic Epithelial Cells and Their Derived Exosomes Protect Against Cisplatin-Induced Acute Kidney Injury Without Compromising Its Antitumor Activity in Mice

Xin Kang, Ying Chen, Xiaohong Xin, +10

Frontiers in Cell and Developmental Biology

Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro

Xinyuan Lai, Chuanyun Li, Chengang Xiang, +13

Stem Cell Reports

Liver FibrosisAdult Stem CellImmunologyBiomedical EngineeringFunctional Ihscs +23

Human Amnion Epithelial Cells and Their Derived Exosomes Alleviate Sepsis-Associated Acute Kidney Injury via Mitigating Endothelial Dysfunction

Dongxuan Chi, Ying Chen, Chengang Xiang, +10

Frontiers in Medicine

Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor

Qi Yu, Ying Chen, Youlu Zhao, +10

Kidney Diseases