Control of dynamic CFTR selectivity by glutamate and ATP in epithelial cells

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng, Richard J. Gregory, John Marshall et al. · Cell · 1990 · 1.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Nucleoside triphosphates are required to open the CFTR chloride channel

Matthew P. Anderson, Herbert A. Berger, Devra P. Rich et al. · Cell · 1991 · 525 citations

Natural Sciences, Cell Biology, Molecular Biology +13

Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In <i>Xenopus</i> Oocytes

Mitchell L. Drumm, Daniel J. Wilkinson, Lisa S. Smit et al. · Science · 1991 · 499 citations

Life Sciences, Genetics, Molecular Biology +17

Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties

David N. Sheppard, Devra P. Rich, Lynda S. Ostedgaard et al. · Nature · 1993 · 466 citations

Natural Sciences, Genetics, Molecular Genetics +13