Lynda S. Ostedgaard

Disruption of the <i>CFTR</i> Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

Christopher S. Rogers, David A. Stoltz, David K. Meyerholz et al. · Science · 2008 · 740 citations

Genetics, Immunology, Gastroenterology +17

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

David A. Stoltz, David K. Meyerholz, Alejandro A. Pezzulo et al. · Science Translational Medicine · 2010 · 484 citations · Full text

Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties

David N. Sheppard, Devra P. Rich, Lynda S. Ostedgaard et al. · Nature · 1993 · 464 citations

Fibrosis, Signal Transduction, Molecular Physiology +9

A C-terminal motif found in the β ₂ -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na ⁺ /H ⁺ exchanger regulatory factor family of PDZ proteins

Randy A. Hall, Lynda S. Ostedgaard, Richard T. Premont et al. · Proceedings of the National Academy of Sciences · 1998 · 402 citations

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

Mark J. Hoegger, Anthony J. Fischer, James D. McMenimen et al. · Science · 2014 · 368 citations