A Neonatal Swine Model of Allergy Induced by the Major Food Allergen Chicken Ovomucoid (Gal d 1)

Abstract

The present results confirm induction of Ovm-specific allergy in pigs and provide opportunity to investigate allergic predisposition and immunopathogenesis of IgE-induced Ovm allergy using outbred neonatal swine. This may better simulate allergic disease in humans and allow investigation of candidate prophylactic and therapeutic approaches.